RNA Fibers as Optimized Nanoscaffolds for siRNA Coordination and Reduced Immunological Recognition
نویسندگان
چکیده
منابع مشابه
RNA کوچک مداخله گر(siRNA)
بیماری‌های عفونی ناشی از میکروارگانیسم‌ها هم‌چنان به‌عنوان علل عمده مرگ در سراسر جهان مطرح بوده و افزایش تعداد سویه‌های مقاوم آن‌ها باعث نگرانی زیادی شده است. از زمان کشف خاموشی ژن توسط RNA (RNAi) انقلابی در زمینه کاربرد درمانی آن به‌راه افتاده است. استفاده از RNA مداخله‌گر پتانسیل درمانی بسیاری برای درمان یا پیش‌گیری از بیماری‌ها دارد. این RNA ها نقش‌های حیاتى در تنظیم رونویسى و پس از رونویسى،...
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ژورنال
عنوان ژورنال: Advanced Functional Materials
سال: 2018
ISSN: 1616-301X,1616-3028
DOI: 10.1002/adfm.201805959